Interspecies Comparison of Human and Murine Scleroderma Reveals IL-13 and CCL2 as Disease Subset-Specific Targets

Development of personalized treatment regimens is hampered by lack of insight into how individual animal models reflect subsets of human disease, and autoimmune and inflammatory conditions have proven resistant to such efforts. Scleroderma is a lethal autoimmune disease characterized by fibrosis, wi...

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Main Authors: Greenblatt, Matthew B., Sargent, Jennifer L., Farina, Giuseppina, Tsang, Kelly, Lafyatis, Robert, Glimcher, Laurie H., Whitfield, Michael L., Aliprantis, Antonios O.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349888/
https://ncbi.nlm.nih.gov/pubmed/22245215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.11.024
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