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Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13
Tissue remodeling with fibrosis is a predominant pathophysiological mechanism of many human diseases. Systemic sclerosis is a rare, often lethal, disorder of unknown etiology manifested by dermal fibrosis (scleroderma) and excessive connective tissue deposition in internal organs. Currently, there a...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815266/ https://ncbi.nlm.nih.gov/pubmed/17307869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700021104 |
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