Tight Skin 2 Mice Exhibit Delayed Wound Healing Caused by Increased Elastic Fibers in Fibrotic Skin

Rationale: The Tight Skin 2 (Tsk2) mouse model of systemic sclerosis (SSc) has many features of human disease, including tight skin, excessive collagen deposition, alterations in the extracellular matrix (ECM), increased elastic fibers, and occurrence of antinuclear antibodies with age. A tight skin...

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Autors principals: Long, Kristen B., Burgwin, Chelsea M., Huneke, Richard, Artlett, Carol M., Blankenhorn, Elizabeth P.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
Matèries:
Discovery Express
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152796/
https://ncbi.nlm.nih.gov/pubmed/25207200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/wound.2014.0529
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