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Covalent Ligand Discovery Against Druggable Hotspots Targeted by Anti-Cancer Natural Products
Many natural products that show therapeutic activities are oftentimes difficult to synthesize or isolate and have unknown targets, hindering their development as drugs. Identifying druggable hotspots targeted by covalently-acting anti-cancer natural products can enable pharmacological interrogation...
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| Publicado no: | Cell Chem Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693770/ https://ncbi.nlm.nih.gov/pubmed/28919038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.08.013 |
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