Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow

Selectins mediate rolling of leukocytes by rapid formation and dissociation of selectin–ligand bonds, which are assumed to require high mechanical strength to prevent premature dissociation by the forces applied in shear flow. This assumption is based largely on the observation that increasing wall...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Ramachandran, Vishwanath, Yago, Tadayuki, Epperson, Terry Kay, Kobzdej, Marcin M. A., Nollert, Matthias U., Cummings, Richard D., Zhu, Cheng, McEver, Rodger P.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 2001
Aiheet:	Biological Sciences
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC56933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11481445/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.171248098
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