Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow
Selectins mediate rolling of leukocytes by rapid formation and dissociation of selectin–ligand bonds, which are assumed to require high mechanical strength to prevent premature dissociation by the forces applied in shear flow. This assumption is based largely on the observation that increasing wall...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC56933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11481445/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.171248098 |
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