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EXTH-17. MEK KINASE INHIBITOR, TRAMETINIB, SUPPRESSES MACROPHAGE-SECRETED TNF-α ON ONCOLYTIC HSV-1 THERAPY, ENHANCING VIROTHERAPY
Oncolytic herpes simplex viruse-1 (oHSV) therapy is currently FDA-approved for advanced melanoma and is currently being evaluated in several clinical trials. However, its clinical success has been limited and various combinatorial treatment modalities are being investigated to enhance the efficacy o...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693209/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.312 |
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