The impact of macrophage and microglia secreted TNFα on oncolytic HSV-1 therapy in the glioblastoma tumor microenvironment

PURPOSE: Oncolytic herpes simplex viruses [oHSV] represent a promising therapy for glioblastoma [GB], but their clinical success has been limited. Early innate immune responses to viral infection reduce oHSV replication, tumor destruction, and efficacy. Here, we characterized the antiviral effects o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Meisen, W Hans, Wohleb, Eric S, Jaime-Ramirez, Alena Cristina, Bolyard, Chelsea, Yoo, Ji Young, Russell, Luke, Hardcastle, Jayson, Dubin, Samuel, Muili, Kamaldeen, Yu, Jianhua, Caligiuri, Michael, Godbout, Jonathan, Kaur, Balveen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780415/
https://ncbi.nlm.nih.gov/pubmed/25829396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3118
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia