BAI1 orchestrates macrophage inflammatory response to HSV infection- implications for oncolytic viral therapy

PURPOSE: Brain Angiogenesis Inhibitor (BAI1) facilitates phagocytosis, and bacterial pathogen clearance by macrophages; however, its role in viral infections is unknown. Here we examined the role of BAI1, and its N-terminal cleavage fragment (Vstat120) in antiviral macrophage responses to oncolytic...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Bolyard, Chelsea, Meisen, W. Hans, Banasavadi-Siddegowda, Yeshavanth, Hardcastle, Jayson, Yoo, Ji Young, Wohleb, Eric S., Wojton, Jeffrey, Yu, Jun-Ge, Dubin, Samuel, Khosla, Maninder, Xu, Bo, Smith, Jonathon, Alvarez-Breckenridge, Christopher, Pow-anpongkul, Pete, Pichiorri, Flavia, Zhang, Jianying, Old, Matthew, Zhu, Dan, Van Meir, Erwin G., Godbout, Jonathan P., Caligiuri, Michael A., Yu, Jianhua, Kaur, Balveen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380537/
https://ncbi.nlm.nih.gov/pubmed/27852701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1818
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