Humanized Chondroitinase ABC Sensitizes Glioblastoma Cells to Temozolomide

INTRODUCTION: Malignant gliomas (GBMs) are extremely aggressive and have a median survival of approximately 15 months. Current treatment modalities, which include surgical resection, radiation and chemotherapy, have done little to prolong the lives of GBM patients. Chondroitin sulfate proteoglycans...

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Detalhes bibliográficos
Publicado no:J Gene Med
Main Authors: Jaime-Ramirez, Alena Cristina, Dmitrieva, Nina, Yoo, Ji Young, Banasavadi-Siddegowda, Yeshavanth, Zhang, Jianying, Relation, Theresa, Bolyard-Blessing, Chelsea, Wojton, Jeffrey, Kaur, Balveen
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382089/
https://ncbi.nlm.nih.gov/pubmed/28087981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.2942
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