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Oncolytic HSV-1 Virotherapy: Clinical Experience and Opportunities for Progress

Oncolytic virotherapy with mutants derived from Herpes simplex virus (HSV) type 1 exhibit significant antitumor effects in preclinical models. Several mutants have now been tested in clinical trials for a variety of cancer types, and all have been found to be safe. While there have been hints of ant...

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Publicat a:Curr Pharm Biotechnol
Autors principals: Kaur, Balveen, Chiocca, E. Antonio, Cripe, Timothy P
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233127/
https://ncbi.nlm.nih.gov/pubmed/21740359
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