STAT3 Activation Promotes Oncolytic HSV1 Replication in Glioma Cells

Recent studies report that STAT3 signaling is a master regulator of mesenchymal transformation of gliomas and that STAT3 modulated genes are highly expressed in the mesenchymal transcriptome of gliomas. A currently studied experimental treatment for gliomas consists of intratumoral injection of onco...

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Bibliographic Details
Main Authors: Okemoto, Kazuo, Wagner, Benjamin, Meisen, Hans, Haseley, Amy, Kaur, Balveen, Chiocca, Ennio Antonio
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732216/
https://ncbi.nlm.nih.gov/pubmed/23936533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071932
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