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PDTM-49. GLOBAL REDUCTION IN H3K27me3, SIMILAR TO H3K27M MUTANT GLIOMAS, IS A MOLECULAR SURROGATE FOR PEDIATRIC POSTERIOR FOSSA- GROUP A EPENDYMOMAS

Ependymomas in children occur most commonly in the posterior fossa of the brain and cause significant morbidity and mortality. The pathogenesis of these tumors remains obscure as recent whole genome and whole exome sequencings have not yielded recurrent genetic alterations. These tumors are classifi...

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Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Vennneti, Sriram, Panwalkar, Pooja, Clark, Jonathan, Ramaswamy, Vijay, Hawes, Debra, Yang, Fusheng, Dunham, Christopher, Yip, Stephen, Hukin, Juliette, Sun, Yilun, Schipper, Matthew, Chavez, Lukas, Margol, Ashley, Pekmezci, Melike, Chung, Chan, Banda, Adam, Bayliss, Jill, Curry, Sarah, Santi, Mariarita, Rodriguez, Fausto, Snuderl, Matija, Karajannis, Matthias, Saratsis, Amanda, Horbinski, Craig M, Kool, Marcel, Pfister, Stefan M, Taylor, Michael, Hawkins, Cynthia, Korshunov, Andrey, Judkins, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693194/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.811
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