PDTM-49. GLOBAL REDUCTION IN H3K27me3, SIMILAR TO H3K27M MUTANT GLIOMAS, IS A MOLECULAR SURROGATE FOR PEDIATRIC POSTERIOR FOSSA- GROUP A EPENDYMOMAS

Ependymomas in children occur most commonly in the posterior fossa of the brain and cause significant morbidity and mortality. The pathogenesis of these tumors remains obscure as recent whole genome and whole exome sequencings have not yielded recurrent genetic alterations. These tumors are classifi...

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Publicado no:Neuro Oncol
Main Authors: Vennneti, Sriram, Panwalkar, Pooja, Clark, Jonathan, Ramaswamy, Vijay, Hawes, Debra, Yang, Fusheng, Dunham, Christopher, Yip, Stephen, Hukin, Juliette, Sun, Yilun, Schipper, Matthew, Chavez, Lukas, Margol, Ashley, Pekmezci, Melike, Chung, Chan, Banda, Adam, Bayliss, Jill, Curry, Sarah, Santi, Mariarita, Rodriguez, Fausto, Snuderl, Matija, Karajannis, Matthias, Saratsis, Amanda, Horbinski, Craig M, Kool, Marcel, Pfister, Stefan M, Taylor, Michael, Hawkins, Cynthia, Korshunov, Andrey, Judkins, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693194/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.811
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