IMMU-15. PD-1 BLOCKADE ACTIVATES CD4 T CELLS AND THE INNATE IMMUNE RESPONSE FOR GLIOBLASTOMA ERADICATION

Blockade of immune cell co-inhibitory receptor PD-1 using monoclonal antibodies (mAbs) allows the development of anti-tumor immunity in various solid tumors and lymphoid malignancies. We recently demonstrated that PD-1 blockade elicits an anti-tumor immune response resulting in tumor rejection and l...

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Vydáno v:Neuro Oncol
Hlavní autoři: Klein, Sarah R, Speranza, Maria Carmela, Gokhale, Prafulla C, Wilkens, Margaret K, Jones, Kristen L, Kirschmeier, Paul T, Chaudhri, Apoorvi, Reardon, David, Freeman, Gordon J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693073/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.474
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