IMMU-28. DEFINING MOLECULAR MECHANISMS OF RESISTANCE TO GLIOBLASTOMA (GBM) IMMUNITY USING A NOVEL CRISPR/CAS9 IN VIVO LOSS-OF-FUNCTION SCREENING PLATFORM

OBJECTIVE: Developing a high-throughput, in vivo, loss-of-function screening platform for GBM immune-escape mechanisms and identifying novel immuno-therapy targets. BACKGROUND: While recent success of cancer immunotherapy asserts the importance of immune-mediated tumor eradication, patients respond...

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Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Neagu, Martha R, Speranza, Maria Carmela, Manguso, Robert T, Lawler, Sean E, Freeman, Gordon J, Doench, John, Sharpe, Arlene H, Haining, W Nicholas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Abstracts
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693027/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.486
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