Lanean...
EXTH-08. DISCOVERY OF CT-179: A SMALL MOLECULE INHIBITOR OF THE OLIG2 TRANSCRIPTION FACTOR WITH POTENT ANTI-TUMOUR ACTIVITY IN HIGH-GRADE GLIOMA
OLIG2 is a protein transcription factor (TF) expressed exclusively in progenitor cells in the brain and spinal cord during development and is re-expressed in most high-grade glioma (HGG) patients. Expression of OLIG2 drives the growth, invasiveness, and resistance to radiation of HGG cells and tumor...
Gorde:
| Argitaratua izan da: | Neuro Oncol |
|---|---|
| Egile nagusia: | |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2017
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692999/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.304 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|