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CADD-17. CT-179: AN INHIBITOR OF THE OLIG2 TRANSCRIPTION FACTOR WITH POTENT ANTI-TUMOUR ACTIVITY IN BRAIN CANCER

High Grade Glioma (HGG) is incurable and has a median survival of less than 5% at five years, highlighting a desperate need for new therapeutic strategies. OLIG2 is a basic helix-loop-helix (bHLH) transcription factor that is expressed in neural progenitor cells during embryonic development where it...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Autor Principal: Johns, Terrance
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216824/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1162
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