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EXTH-18. CT-179 SELECTIVELY TARGETS OLIG2-POSITIVE GLIOMA STEM CELLS AND DEMONSTRATES POTENT ANTI-TUMOR ACTIVITY IN GLIOBLASTOMA
Olig2 is a lineage-specific bHLH transcription factor in normal brain development and has been shown to be a critical oncogene controlling the tumorigenesis, growth, invasion, differentiation and radiation resistance of gliomas, including glioblastoma (GBM). Importantly, Olig2-positive glioma stem-l...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5691953/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.313 |
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