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DDIS-19. CT-179: AN INHIBITOR OF THE OLIG2 TRANSCRIPTION FACTOR WITH POTENT ANTI-TUMOUR ACTIVITY IN BRAIN CANCER

High Grade Glioma (HGG) is incurable and has a median survival of less than 5% at five years, highlighting a desperate need for new therapeutic strategies. OLIG2 is a basic helix-loop-helix (bHLH) transcription factor that is expressed in neural progenitor cells during embryonic development where it...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Johns, Terrance, Greenall, Sameer, Chen, Shengnan, Stewart, Rodney, Alton, Gordon, Kesari, Santosh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216246/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.298
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