載入...
EXTH-08. DISCOVERY OF CT-179: A SMALL MOLECULE INHIBITOR OF THE OLIG2 TRANSCRIPTION FACTOR WITH POTENT ANTI-TUMOUR ACTIVITY IN HIGH-GRADE GLIOMA
OLIG2 is a protein transcription factor (TF) expressed exclusively in progenitor cells in the brain and spinal cord during development and is re-expressed in most high-grade glioma (HGG) patients. Expression of OLIG2 drives the growth, invasiveness, and resistance to radiation of HGG cells and tumor...
Na minha lista:
| 發表在: | Neuro Oncol |
|---|---|
| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2017
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692999/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.304 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|