EXTH-53. IMPACT OF EGFRvIII AND PTEN DELETION MUTATIONS ON RESPONSE OF Ink4a/Arf-NULL MURINE ASTROCYTES TO EGFR TYROSINE KINASE INHIBITORS

Epidermal growth factor receptor (EGFR) represents the most attractive target for personalized medicine of glioblastoma (GBM) due to its frequency in and specificity for the disease, and the availability of multiple inhibitors that target its tyrosine kinase domain. Despite its therapeutic attractiv...

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發表在:Neuro Oncol
Main Authors: Smithberger, Erin, Flores, Alex, Dhruv, Harshil, Johnson, Gary, Berens, Michael, Furnari, Frank, Miller, C Ryan
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692991/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.345
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