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EXTH-53. IMPACT OF EGFRvIII AND PTEN DELETION MUTATIONS ON RESPONSE OF Ink4a/Arf-NULL MURINE ASTROCYTES TO EGFR TYROSINE KINASE INHIBITORS

Epidermal growth factor receptor (EGFR) represents the most attractive target for personalized medicine of glioblastoma (GBM) due to its frequency in and specificity for the disease, and the availability of multiple inhibitors that target its tyrosine kinase domain. Despite its therapeutic attractiv...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Smithberger, Erin, Flores, Alex, Dhruv, Harshil, Johnson, Gary, Berens, Michael, Furnari, Frank, Miller, C Ryan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692991/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.345
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