EXTH-53. IMPACT OF EGFRvIII AND PTEN DELETION MUTATIONS ON RESPONSE OF Ink4a/Arf-NULL MURINE ASTROCYTES TO EGFR TYROSINE KINASE INHIBITORS

Epidermal growth factor receptor (EGFR) represents the most attractive target for personalized medicine of glioblastoma (GBM) due to its frequency in and specificity for the disease, and the availability of multiple inhibitors that target its tyrosine kinase domain. Despite its therapeutic attractiv...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuro Oncol
मुख्य लेखकों: Smithberger, Erin, Flores, Alex, Dhruv, Harshil, Johnson, Gary, Berens, Michael, Furnari, Frank, Miller, C Ryan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2017
विषय:
Abstracts
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692991/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.345
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