METB-16. ACQUISITION OF WARBURG PHENOTYPE IN IDH1-MUTATED GLIOMA AS A MECHANISM OF MALIGNANT TRANSFORMATION

BACKGROUND: The Warburg effect is one of the hallmarks of cancer metabolism and its prevalence includes gliomas. The formation of lactate and upregulation of glycolysis has been the basis of many studies that either use (18)FDG PET or lactate as a readout of cancer progression. However, IDH1-mutated...

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Publicado en:Neuro Oncol
Autores principales: Rodado, Victor Ruiz, Seki, Tomohiro, Dowdy, Tyrone, Lita, Adrian, Celiku, Orieta, Yamamoto, Kazu, Saito, Keita, Saldana, Alejandra Cavazos, Li, Aiguo, Cherukuri, Murali Krishna, Gilbert, Mark, Larion, Mioara
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692799/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.539
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