METB-16. ACQUISITION OF WARBURG PHENOTYPE IN IDH1-MUTATED GLIOMA AS A MECHANISM OF MALIGNANT TRANSFORMATION

BACKGROUND: The Warburg effect is one of the hallmarks of cancer metabolism and its prevalence includes gliomas. The formation of lactate and upregulation of glycolysis has been the basis of many studies that either use (18)FDG PET or lactate as a readout of cancer progression. However, IDH1-mutated...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Rodado, Victor Ruiz, Seki, Tomohiro, Dowdy, Tyrone, Lita, Adrian, Celiku, Orieta, Yamamoto, Kazu, Saito, Keita, Saldana, Alejandra Cavazos, Li, Aiguo, Cherukuri, Murali Krishna, Gilbert, Mark, Larion, Mioara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692799/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.539
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