ロード中...
EXTH-61. TARGETED NANOPARTICLE DELIVERY OF THERAPEUTIC ANTIMIR-21 AND ANTIMIR-10B PRESENSITIZES GLIOBLASTOMA TO LOWER EFFECTIVE DOSES OF TEMOZOLOMIDE IN CELLS AND XENOGRAFTS
BACKGROUND: MiR-21 and miR-10b are oncomiRs overexpressed in glioblastoma (GBM). Therapeutic antisense microRNAs (antimiRs) can effectively initiate cellular apoptosis. We hypothesized that encapsulating antimiR-21 and antimiR-10b into c-RGD peptide surface tagged PLGA nanoparticles (NPs) would lead...
保存先:
| 出版年: | Neuro Oncol |
|---|---|
| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2017
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692759/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.353 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|