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PDTM-16. IDENTIFICATION OF NOVEL EPIGENETIC DRUG COMBINATIONS WITH SYNERGISTIC INHIBITORY EFFECTS AGAINST MYC-AMPLIFIED GROUP 3 MEDULLOBLASTOMA

Medulloblastoma is the most common type of malignant pediatric brain tumor. It can be categorized into 4 major subgroups with distinct biological and clinical signatures: WNT, SHH, Group 3 and Group 4. MYC-amplified Group 3 medulloblastoma tend to metastasis and have the worst prognosis, however, th...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Zhang, Lei, Li, Meng, Sui, Yi, Liu, Fang, Jiang, Wenyan, Li, Tiantian, Tang, Yujie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692679/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.780
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