Effective Inhibition of MYC-Amplified Group 3 Medulloblastoma Through Targeting EIF4A1

PURPOSE: In medulloblastoma (MB), group 3 (G3) patients with MYC amplification tend to exhibit worse prognosis, thus creating a need for novel effective therapies. As the driver and crucial dependency for MYC-amplified G3-MB, MYC has been proven to be a prospective therapeutic target. Here, we aimed...

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Dades bibliogràfiques
Publicat a:Cancer Manag Res
Autors principals: Zhao, Yang, Li, Tiantian, Tian, Shuaiwei, Meng, Wei, Sui, Yi, Yang, Jian, Wang, Baocheng, Liang, Zhuangzhuang, Zhao, Heng, Han, Yipeng, Tang, Yujie, Zhang, Lei, Ma, Jie
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721120/
https://ncbi.nlm.nih.gov/pubmed/33299354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S278844
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