PDTM-13. OVEREXPRESSION OF MYC ALONE IS SUFFICIENT TO INITIATE GROUP 3 MEDULLOBLASTOMA

Medulloblastoma (MB) is the most common malignant brain tumor in children. Among the four molecular subgroups of MB (WNT, SHH, Group 3 and Group 4), patients with Group 3 MB exhibit the worst prognosis. Group 3 MB is associated with amplification and overexpression of the MYC oncogene. However, whet...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Tao, Ran, Murad, Najiba, Xu, Zhenhua, Zhang, Peng, Okonechnikov, Konstantin, Kool, Marcel, Rivero-Hinojosa, Samuel, Lazarski, Christopher, Zheng, Pan, Eberhart, Charles, Rood, Brian, Packer, Roger, Pei, Yanxin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217641/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.855
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