EMBR-02. OLIG2 REPRESENTS A PROGNOSTIC MARKER AND THERAPEUTIC TARGET IN MYC-AMPLIFIED MEDULLOBLASTOMA RELAPSE AND METASTASIS

Medulloblastoma (MB) is one of the most common malignant pediatric brain tumors. Among the multiple MB subtypes, MB with MYC amplification confers an extremely poor prognosis with an overall survival rate of less than 30%. Relapse is often mediated by a small population of therapy-resistant tumor ce...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Xu, Zhenhua, Murad, Najiba, Rivero-Hinojosa, Samuel, Schüller, Ulrich, Zhang, Peng, Liu, Xiao, Rood, Brian, Packer, Roger, Pei, Yanxin
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2021
Предметы:
Embryonal Tumors
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168222/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.020
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