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EMBR-02. OLIG2 REPRESENTS A PROGNOSTIC MARKER AND THERAPEUTIC TARGET IN MYC-AMPLIFIED MEDULLOBLASTOMA RELAPSE AND METASTASIS

Medulloblastoma (MB) is one of the most common malignant pediatric brain tumors. Among the multiple MB subtypes, MB with MYC amplification confers an extremely poor prognosis with an overall survival rate of less than 30%. Relapse is often mediated by a small population of therapy-resistant tumor ce...

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Publicado en:Neuro Oncol
Autores principales: Xu, Zhenhua, Murad, Najiba, Rivero-Hinojosa, Samuel, Schüller, Ulrich, Zhang, Peng, Liu, Xiao, Rood, Brian, Packer, Roger, Pei, Yanxin
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168222/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.020
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