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PDTM-41. TG02, A NOVEL MULTIKINASE INHIBITOR, IS EFFECTIVE IN PEDIATRIC BRAIN TUMORS, WITH SELECTIVE POTENCY IN THOSE WITH MYC EXPRESSION
Brain tumors account for the most cancer-related deaths among children. MYC is one of the key oncogenes implicated in the tumor pathogenesis, and MYC (c-MYC, MYCN, and MYCL) deregulation is common in various types of malignant brain tumors in children, including those with the worst prognoses. Subse...
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| Publicat a: | Neuro Oncol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692377/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.804 |
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