PDTM-46. TARGETING METABOLIC ADAPTATION IN MYC DRIVEN PEDIATRIC NEURONAL TUMORS

BACKGROUND/OBJECTIVES: MYC family proteins are implicated in many human cancers, but their therapeutic targeting has proven challenging. MYCN and c-MYC amplification in childhood neuroblastoma (NB) and medulloblastoma (MB) are associated with aggressive disease and high mortality. Novel and effectiv...

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Publicado no:Neuro Oncol
Main Authors: Delaidelli, Alberto, Negri, Gian Luca, Jan, Asad, Jansonius, Brandon, Lim, Jonathan K M, Leprivier, Gabriel, Kool, Marcel, Pfister, Stefan M, Remke, Marc, Taylor, Michael, Maris, John M, Sorensen, Poul H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692001/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.808
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