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CBMT-05. ROLE OF THE let7-eEF2K AXIS IN MYC-DRIVEN MEDULLOBLASTOMA ADAPTATION TO NUTRIENT DEPRIVATION
BACKGROUND/OBJECTIVES: MYC amplification in medulloblastoma (MB) determines highly aggressive disease, underscoring an urgent need for novel therapies. Let-7 microRNAs (miRNAs) inhibit tumor progression and regulate metabolism by degrading several mRNAs, including MYC. Let-7 miRNAs are frequently re...
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| Yayımlandı: | Neuro Oncol |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216938/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.124 |
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