MBRS-57. TARGETING METABOLIC ADAPTATION IN MYC/MYCN AMPLIFIED PEDIATRIC MEDULLOBLASTOMA AND NEUROBLASTOMA

BACKGROUND: The MYC oncogenes contribute to more than 50% of all human cancers, but their therapeutic targeting has proven challenging. MYC/MYCN amplification in childhood medulloblastoma (MB) and neuroblastoma (NB) determine aggressive disease and high mortality, underlying the need for novel and e...

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Publicat a:Neuro Oncol
Autors principals: Delaidelli, Alberto, Negri, Gian Luca, Sidhu, Simran, Cran, Jordan, Remke, Marc, Pfister, Stefan, Kool, Marcel, Taylor, Michael, Maris, John, Leprivier, Gabriel, Sorensen, Poul
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012866/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.501
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