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PDTM-27. DIANHYDROGALACTITOL (VAL-083) OVERCOMES CHEMORESISTANCE IN PEDIATRIC MALIGNANT BRAIN TUMORS AND DISPLAYS SYNERGY WITH TOPOISOMERASE INHIBITORS

More children die from brain cancer than from any other disease. Medulloblastoma (MB) and pediatric high-grade gliomas (pHGG) are the most common malignant brain cancers in children. Children with pHGG have few therapeutic options and 5-year survival is less than 20%. Treatment includes surgery, rad...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Zhai, Beibei, Steino, Anne, Bacha, Jeffrey, Brown, Dennis, Zhang, Jie, Nicolaides, Theo, Daugaard, Mads
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693124/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.791
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