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HGG-02. DIANHYDROGALACTITOL (VAL-083) OVERCOMES MGMT- AND P53-MEDIATED CHEMO-RESISTANCE AND DISPLAYS SYNERGY WITH TOPOISOMERASE INHIBITORS
The mortality rate of pediatric CNS cancer has not decreased as other pediatric cancers, and high-grade gliomas (HGG) are the main cause of death in children with brain tumors. Children with HGG have few therapeutic options and 5-year survival is less than 20%. Relapsed HGG have a uniformly fatal ou...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475066/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.091 |
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