SURG-24. OVERALL SURVIVAL IN A SYNGENEIC RODENT ORTHOTOPIC HIGH-GRADE GLIOMA MODEL IS SIGNIFICANTLY PROLONGED BY NEUROSURGICAL DELIVERY OF PLGA/PEG INTERSTITIAL CHEMOTHERAPY

INTRODUCTION: The blood brain barrier is a critical limiting step to achieving therapeutic CNS drug concentrations. We have developed a poly(lactic-co-glycolic acid)/poly(ethylene glycol) (PLGA/PEG)-based platform technology to interstitially deliver multiple chemotherapy agents from a single thermo...

詳細記述

保存先:
書誌詳細
出版年:Neuro Oncol
主要な著者: Smith, Stuart, Gould, Toby, Tyler, Betty, Ritchie, Alison, Veal, Gareth, Shakesheff, Kevin, Brem, Henry, Grundy, Richard, Rahman, Ruman
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
Abstracts
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692184/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.979
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