Overall survival in an orthotopic GBM model is significantly prolonged by neurosurgical delivery of PLGA/PEG interstitial chemotherapy

INTRODUCTION: The blood brain barrier is a critical limiting step to achieving therapeutic CNS drug concentrations. We have developed a poly(lactic-co-glycolic acid)/poly(ethylene glycol) (PLGA/PEG)-based platform technology to interstitially deliver multiple chemotherapy agents from a single thermo...

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Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Smith, Stuart, Gould, Toby, Tyler, Betty, Ritchie, Alison, Veal, Gareth, Shakesheff, Kevin, Brem, Henry, Grundy, Richard, Rahman, Ruman
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
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Abstracts
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791675/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox237.025
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