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Conservation and divergence of p53 oscillation dynamics across species

The tumor suppressing transcription factor p53 is highly conserved at the protein level and plays a key role in the DNA damage response. One important aspect of p53 regulation is its dynamics in response to DNA damage, which include oscillations. Here, we observe that while the qualitative oscillato...

詳細記述

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書誌詳細
出版年:Cell Syst
主要な著者: Stewart-Ornstein, Jacob, Cheng, Ho Wa (Jacky), Lahav, Galit
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687840/
https://ncbi.nlm.nih.gov/pubmed/29055670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.09.012
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