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p53 pulses lead to distinct patterns of gene expression albeit similar DNA binding dynamics
The dynamics of transcription factors play important roles in a variety of biological systems. However, the mechanisms by which these dynamics are decoded into different transcriptional responses are not well understood. Here we focus on the dynamics of the tumor suppressor protein p53, which exhibi...
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| Udgivet i: | Nat Struct Mol Biol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5629117/ https://ncbi.nlm.nih.gov/pubmed/28825732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3452 |
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