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p53 pulses lead to distinct patterns of gene expression albeit similar DNA binding dynamics

The dynamics of transcription factors play important roles in a variety of biological systems. However, the mechanisms by which these dynamics are decoded into different transcriptional responses are not well understood. Here we focus on the dynamics of the tumor suppressor protein p53, which exhibi...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Hafner, Antonina, Stewart-Ornstein, Jacob, Purvis, Jeremy E., Forrester, William C., Bulyk, Martha L., Lahav, Galit
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629117/
https://ncbi.nlm.nih.gov/pubmed/28825732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3452
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