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p53 pulses lead to distinct patterns of gene expression albeit similar DNA binding dynamics

The dynamics of transcription factors play important roles in a variety of biological systems. However, the mechanisms by which these dynamics are decoded into different transcriptional responses are not well understood. Here we focus on the dynamics of the tumor suppressor protein p53, which exhibi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Struct Mol Biol
Egile Nagusiak: Hafner, Antonina, Stewart-Ornstein, Jacob, Purvis, Jeremy E., Forrester, William C., Bulyk, Martha L., Lahav, Galit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629117/
https://ncbi.nlm.nih.gov/pubmed/28825732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3452
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