Identification of universal and cell-type specific p53 DNA binding

BACKGROUND: The tumor suppressor p53 is a major regulator of the DNA damage response and has been suggested to selectively bind and activate cell-type specific gene expression programs. However recent studies and meta-analyses of genomic data propose largely uniform, and condition independent p53 bi...

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Udgivet i:BMC Mol Cell Biol
Main Authors: Hafner, Antonina, Kublo, Lyubov, Tsabar, Michael, Lahav, Galit, Stewart-Ornstein, Jacob
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027055/
https://ncbi.nlm.nih.gov/pubmed/32070277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00251-8
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