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Conservation and divergence of p53 oscillation dynamics across species

The tumor suppressing transcription factor p53 is highly conserved at the protein level and plays a key role in the DNA damage response. One important aspect of p53 regulation is its dynamics in response to DNA damage, which include oscillations. Here, we observe that while the qualitative oscillato...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Stewart-Ornstein, Jacob, Cheng, Ho Wa (Jacky), Lahav, Galit
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687840/
https://ncbi.nlm.nih.gov/pubmed/29055670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.09.012
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