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Ca(2+) signals initiate at immobile IP(3) receptors adjacent to ER-plasma membrane junctions
IP(3) receptors (IP(3)Rs) release Ca(2+) from the ER when they bind IP(3) and Ca(2+). The spatial organization of IP(3)Rs determines both the propagation of Ca(2+) signals between IP(3)Rs and the selective regulation of cellular responses. Here we use gene editing to fluorescently tag endogenous IP(...
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| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5686115/ https://ncbi.nlm.nih.gov/pubmed/29138405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01644-8 |
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