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KRAP tethers IP(3) receptors to actin and licenses them to evoke cytosolic Ca(2+) signals

Regulation of IP(3) receptors (IP(3)Rs) by IP(3) and Ca(2+) allows regenerative Ca(2+) signals, the smallest being Ca(2+) puffs, which arise from coordinated openings of a few clustered IP(3)Rs. Cells express thousands of mostly mobile IP(3)Rs, yet Ca(2+) puffs occur at a few immobile IP(3)R cluster...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Thillaiappan, Nagendra Babu, Smith, Holly A., Atakpa-Adaji, Peace, Taylor, Colin W.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302619/
https://ncbi.nlm.nih.gov/pubmed/34301929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24739-9
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