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KRAP tethers IP(3) receptors to actin and licenses them to evoke cytosolic Ca(2+) signals
Regulation of IP(3) receptors (IP(3)Rs) by IP(3) and Ca(2+) allows regenerative Ca(2+) signals, the smallest being Ca(2+) puffs, which arise from coordinated openings of a few clustered IP(3)Rs. Cells express thousands of mostly mobile IP(3)Rs, yet Ca(2+) puffs occur at a few immobile IP(3)R cluster...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8302619/ https://ncbi.nlm.nih.gov/pubmed/34301929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24739-9 |
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