Ca(2+) signals initiate at immobile IP(3) receptors adjacent to ER-plasma membrane junctions

IP(3) receptors (IP(3)Rs) release Ca(2+) from the ER when they bind IP(3) and Ca(2+). The spatial organization of IP(3)Rs determines both the propagation of Ca(2+) signals between IP(3)Rs and the selective regulation of cellular responses. Here we use gene editing to fluorescently tag endogenous IP(...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Thillaiappan, Nagendra Babu, Chavda, Alap P., Tovey, Stephen C., Prole, David L., Taylor, Colin W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686115/
https://ncbi.nlm.nih.gov/pubmed/29138405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01644-8
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