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Sustained signalling by PTH modulates IP(3) accumulation and IP(3) receptors through cyclic AMP junctions
Parathyroid hormone (PTH) stimulates adenylyl cyclase through type 1 PTH receptors (PTH(1)R) and potentiates the Ca(2+) signals evoked by carbachol, which stimulates formation of inositol 1,4,5-trisphosphate (IP(3)). We confirmed that in HEK cells expressing PTH(1)R, acute stimulation with PTH(1-34)...
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| Udgivet i: | J Cell Sci |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294780/ https://ncbi.nlm.nih.gov/pubmed/25431134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.163071 |
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