Selective coupling of type 6 adenylyl cyclase with type 2 IP(3) receptors mediates direct sensitization of IP(3) receptors by cAMP

Interactions between cyclic adenosine monophosphate (cAMP) and Ca(2+) are widespread, and for both intracellular messengers, their spatial organization is important. Parathyroid hormone (PTH) stimulates formation of cAMP and sensitizes inositol 1,4,5-trisphosphate receptors (IP(3)R) to IP(3). We sho...

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Main Authors: Tovey, Stephen C., Dedos, Skarlatos G., Taylor, Emily J.A., Church, Jarrod E., Taylor, Colin W.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2008
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568025/
https://ncbi.nlm.nih.gov/pubmed/18936250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803172
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