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Compartmentalized cAMP Generation by Engineered Photoactivated Adenylyl Cyclases
Since small molecule activators of adenylyl cyclases (AC) impact ACs cell-wide, it is challenging the explore the signaling consequences of AC activity emanating from specific intracellular compartments. We explored this issue using a series of engineered, optogenetic, spatially-restricted, photoact...
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| Published in: | Cell Chem Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800631/ https://ncbi.nlm.nih.gov/pubmed/31353320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.07.004 |
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